MEFLOQUINE, A CLINICALLY USEFUL QUINOLINE-METHANOL ANTIMALARIAL WHICH DOES NOT SIGNIFICANTLY BIND TO DNA

被引：44

作者：

DAVIDSON, MW ^{[1
]}

GRIGGS, BG ^{[1
]}

BOYKIN, DW ^{[1
]}

WILSON, WD ^{[1
]}

机构：

[1] GEORGIA STATE UNIV,DEPT CHEM,UNIVERSITY PL,ATLANTA,GA 30303

来源：

NATURE | 1975年 / 254卷 / 5501期

关键词：

D O I：

10.1038/254632a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：632 / 634

页数：3

共 21 条

[1]

CARTER G, 1972, P HELM SOC WASH, V39, P244

[2] STRUCTURE AND ANTIMALARIAL ACTIVITY O AMINOALCOHOLS AND 2-(PARA CHLOROPHENYL)-2-(4-PIPERIDYL)TETRAHYDROFURAN [J].

CHENG, CC .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1971, 60 (10) :1596-&

[3]

COHEN SN, 1965, J BIOL CHEM, V240, P3123

[4] ANTIMALARIAL ARYLAMINOPROPANOLS [J].

COLWELL, WT ;

CHRISTIE, P ;

BROWN, V ;

HENRY, DW ;

YAMAMOTO, K ;

REECE, C ;

LANGE, J .

JOURNAL OF MEDICINAL CHEMISTRY, 1972, 15 (07) :771-&

[5] NAPHTHOTHIOPHENES .4. PREPARATION OF MULTISUBSTITUTED 4-NAPHTHO[2,1-B]THIOPHENEMETHANOLS AND EFFECT OF SIDE-CHAIN MODIFICATION ON ANTIMALARIAL ACTIVITY OF 8-TRIFLUOROMETHYL-4-NAPHTHO[2,1-B]THIOPHENEMETHANOLS [J].

DAS, BP ;

NUSS, ME ;

BOYKIN, DW .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (05) :516-519

[6] INTERACTION SPECIFICITY OF NUCLEIC ACIDS [J].

GABBAY, EJ ;

GLASSER, R ;

GAFFNEY, BL .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1970, 171 (03) :810-&

[7] STUDIES ON MODES OF ACTION OF CHLOROQUINE QUINACRINE AND QUININE AND ON CHLOROQUINE RESISTANCE [J].

HAHN, FE ;

OBRIEN, RL ;

CIAK, J ;

ALLISON, JL ;

OLENICK, JG .

MILITARY MEDICINE, 1966, 131 (9S) :1071-&

[8]

HAHN FE, 1969, ANTIMICROBIAL AGENTS, P63

[9]

HENRY DW, 1972, NATL MED CHEM S AM C, V13, P41

[10] THEORY FOR MECHANISM OF CHLOROQUINE RESISTANCE IN RODENT MALARIA [J].

HOWELLS, RE ;

PETERS, W ;

HOMEWOOD, CA ;

WARHURST, DC .

NATURE, 1970, 228 (5272) :625-&

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