HEAVY-CHAIN VARIABLE REGION - MULTIPLE GENE SEGMENTS ENCODE ANTI-4-(HYDROXY-3-NITROPHENYL)ACETYL IDIOTYPIC ANTIBODIES

被引：83

作者：

BOERSCHSUPAN, ME ^{[1
]}

AGARWAL, S ^{[1
]}

WHITESCHARF, ME ^{[1
]}

IMANISHIKARI, T ^{[1
]}

机构：

[1] MIT,DEPT BIOL,CAMBRIDGE,MA 02139

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 1985年 / 161卷 / 06期

关键词：

D O I：

10.1084/jem.161.6.1272

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：1272 / 1292

页数：21

共 48 条

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[2] DIVERSITY AT THE VARIABLE JOINING REGION BOUNDARY OF LAMBDA-LIGHT CHAINS HAS A PRONOUNCED EFFECT ON IMMUNOGLOBULIN LIGAND-BINDING ACTIVITY
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[3] SOMATIC VARIANTS OF MURINE IMMUNOGLOBULIN LAMBDA-LIGHT CHAINS
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[4] HEAVY-CHAIN VARIABLE REGION CONTRIBUTION TO THE NPB FAMILY OF ANTIBODIES - SOMATIC MUTATION EVIDENT IN A GAMMA-2A VARIABLE REGION
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[5] BOTHWELL ALM, 1984, BIOL IDIOTYPES, P19
[6] BRODEUR PH, 1984, EUR J IMMUNOL
[7] ALLELIC IMMUNOGLOBULIN-VH GENES IN 2 MOUSE STRAINS - POSSIBLE GERMLINE GENE RECOMBINATION
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[J]. EMBO JOURNAL, 1983, 2 (11) : 2013 - 2018
[8] A SINGLE VH GENE SEGMENT ENCODES THE IMMUNE-RESPONSE TO PHOSPHORYLCHOLINE - SOMATIC MUTATION IS CORRELATED WITH THE CLASS OF THE ANTIBODY
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[J]. CELL, 1981, 25 (01) : 59 - 66
[9] AN IMMUNOGLOBULIN HEAVY-CHAIN VARIABLE REGION GENE IS GENERATED FROM 3 SEGMENTS OF DNA - VH, D AND JH
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[J]. CELL, 1980, 19 (04) : 981 - 992
[10] IGG ANTIBODIES TO PHOSPHORYLCHOLINE EXHIBIT MORE DIVERSITY THAN THEIR IGM COUNTERPARTS
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[J]. NATURE, 1981, 291 (5810) : 29 - 34

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