REGIONAL SUBLOCALIZATION OF THE HUMAN THYROID PEROXIDASE GENE (TPO) BY TRITIUM AND FLUORESCENCE INSITU HYBRIDIZATION TO CHROMOSOME 2P25-]P24

被引：7

作者：

BARNETT, PS

JONES, TA

MCGREGOR, AM

BANGA, JP

SHEER, D

机构：

[1] UNIV LONDON KINGS COLL,SCH MED & DENT,DEPT MED,LONDON WC2R 2LS,ENGLAND

[2] IMPERIAL CANC RES FUND,HUMAN CYTOGENET LAB,LONDON WC2A 3PX,ENGLAND

来源：

CYTOGENETICS AND CELL GENETICS | 1993年 / 62卷 / 04期

关键词：

D O I：

10.1159/000133471

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Thyroid peroxidase (TPO), the enzyme responsible for thyroid hormone synthesis, is a key autoantigen in autoimmune thyroid disease. Based on the results of a study using both isotopic and nonisotopic in situ hybridization, we assign the gene coding for human TPO to chromosome region 2p25-->p24.

引用

收藏

页码：188 / 189

页数：2

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