SYNTHESIS OF NEW V-TRIAZOLOPYRIMIDINIUM SALTS

被引：11

作者：

BATORI, S

MESSMER, A

机构：

[1] Central Research Institute for Chemistry, Budapest, H-1525

[2] Chinoin Pharmaceutical and Chemical Works Co. Ltd., Budapest, H-1325

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1994年 / 31卷 / 04期

关键词：

D O I：

10.1002/jhet.5570310458

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New v-triazolo[1,5-a]- and v-triazolo[1,5-c]pyrimidinium salts 12a-e, 13a-c have been synthesized via oxidation (i.e. cyclodehydrogenation) of the appropriate pyrimidyl ketone arylhydrazones 3a-e, 6a-c using TBB (2,4,4,6-tetrabromocyclohexa-2,5-dien-1-one) as the reagent. The arylhydrazones were obtained by standard reactions; the Grignard reaction of 2-cyano- and 4-cyanopyrimidine 1a,b, 4a-c gave 2-pyrimidyl- and 4-pyrimidyl ketones 2a-e, 5a-c, which reacted with arylhydrazines to yield the desired ketone arylhydrazones 3a-e, 6a-c.

引用

页码：1041 / 1046

页数：6

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