PREVALENCE OF HUMAN ASTROVIRUS SEROTYPE-4 - CAPSID PROTEIN-SEQUENCE AND COMPARISON WITH OTHER STRAINS

被引:28
作者
WILLCOCKS, MM
KURTZ, JB
LEE, TW
CARTER, MJ
机构
[1] UNIV SURREY,SCH BIOL SCI,GUILDFORD GU2 5XH,SURREY,ENGLAND
[2] JOHN RADCLIFFE HOSP,VIROL LAB,OXFORD OX3 9DU,ENGLAND
关键词
D O I
10.1017/S0950268800058015
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Astrovirus serotype 4 has increased in relative prevalence in the Oxford, UK area in 1993. The structural gene of human astrovirus serotype 4 has been sequenced and the results indicate that this protein differs substantially from serotypes 1 and 2. In particular, conservation at the C terminus is greatly reduced. However, amino acid substitutions in this region show a strong conservation in character suggesting that structural or functional constraints operate in this region.
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页码:385 / 391
页数:7
相关论文
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