STUDIES ON THE INHIBITION OF PORCINE PANCREATIC ELASTASE USING ELECTROSPRAY MASS-SPECTROMETRY

被引：14

作者：

APLIN, RT ^{[1
]}

ROBINSON, CV ^{[1
]}

SCHOFIELD, CJ ^{[1
]}

WESTWOOD, NJ ^{[1
]}

机构：

[1] OXFORD CTR MOLEC SCI,OXFORD OX1 3QY,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 22期

关键词：

D O I：

10.1039/c39920001650

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Electrospray mass spectrometry has been used to investigate the mode of inhibition of porcine pancreatic elastase by chloromethyl ketones and other inhibitors.

引用

页码：1650 / 1652

页数：3

共 14 条

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[2] OBSERVATION OF ENZYME BOUND INTERMEDIATES IN THE BIOSYNTHESIS OF PREUROPORPHYRINOGEN BY PBG DEAMINASE
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[3] SOME ELECTROSPRAY MASS-SPECTROMETRIC EVIDENCE FOR THE EXISTENCE OF COVALENT O-ACYL ENZYME INTERMEDIATES
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[J]. FEBS LETTERS, 1991, 292 (1-2) : 201 - 204
[4] BARRETT AJ, 1981, TXB RHEUMATOLOGY, P195
[5] MASS-SPECTROMETRY
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[J]. ANALYTICAL CHEMISTRY, 1992, 64 (12) : R467 - R502
[6] AN ACYL-CARRIER-PROTEIN-THIOESTERASE DOMAIN FROM THE 6-DEOXYERYTHRONOLIDE-B SYNTHASE OF SACCHAROPOLYSPORA-ERYTHRAEA - HIGH-LEVEL PRODUCTION, PURIFICATION AND CHARACTERIZATION IN ESCHERICHIA-COLI
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[J]. SCIENCE, 1992, 257 (5078) : 1885 - 1894
[8] ORIGIN AND REMOVAL OF ADDUCTS (MOLECULAR MASS = 98-U) ATTACHED TO PEPTIDE AND PROTEIN IONS IN ELECTROSPRAY IONIZATION MASS-SPECTRA
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[J]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1990, 1 (05) : 382 - 388
[9] SULFONYL FLUORIDES AS INHIBITORS OF ESTERASES .1. RATES OF REACTION WITH ACETYLCHOLINESTERASE, ALPHA-CHYMOTRYPSIN, AND TRYPSIN
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