LUPUS NEPHRITIS - VARYING COMPLEMENT-FIXING PROPERTIES OF IMMUNOGLOBULIN G ANTIBODIES TO ANTIGENS OF CELL NUCLEI

被引：99

作者：

TOJO, T

FRIOU, GJ

机构：

[1] Department of Medicine, University of Southern California School of Medicine

来源：

SCIENCE | 1968年 / 161卷 / 3844期

关键词：

D O I：

10.1126/science.161.3844.904

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Relative complement-fixing activity of antibodies to nuclear antigens, including DNA, were determined in serums of 15 patients with, and 65 patients without, active lupus nephritis, by comparing titers obtained in two methods. High complement-fixing activity of antibody was found in the nephritis group and low activity in the others. Results with immunoglobulin G fractions were similar.

引用

页码：904 / &

共 16 条

[1]

COHEN S, 1968, J IMMUNOL, V100, P407

[2]

FAHEY J L, 1967, Methods in Immunology and Immunochemistry, P321

[3]

FRIOU GJ, 1958, J IMMUNOL, V80, P476

[4] IMMUNOLOGICAL STUDIES CONCERNING NEPHRITIS OF SYSTEMIC LUPUS ERYTHEMATOSUS [J].