CHROMATIN DYNAMICS AND THE MODULATION OF GENETIC-ACTIVITY

被引：61

作者：

HANSEN, JC ^{[1
]}

AUSIO, J ^{[1
]}

机构：

[1] UNIV VICTORIA,DEPT BIOCHEM & MICROBIOL,VICTORIA V8W 3P6,BC,CANADA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1992年 / 17卷 / 05期

关键词：

D O I：

10.1016/0968-0004(92)90264-A

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chromatin, the genetic material of eukaryotes, is a dynamic macromolecular assembly that continuously changes its composition and conformation to accommodate different stages of genetic activity, e.g. transcription and replication. Evidence is accumulating that the dynamic behavior of chromatin has important functional roles in the modulation of genetic activity, largely due to the intrinsic properties of arrays of nucleosome cores.

引用

页码：187 / 191

页数：5

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