DIRECTIONALLY ALIGNED HELICAL PEPTIDES ON SURFACES

被引：181

作者：

WHITESELL, JK

CHANG, HK

机构：

[1] Department of Chemistry, University of Texas, Austin

来源：

SCIENCE | 1993年 / 261卷 / 5117期

关键词：

D O I：

10.1126/science.261.5117.73

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Directionally oriented peptide layers 1000 angstroms thick were constructed by polymerization on gold and indium-tin-oxide glass. A key feature is the use of an appropriately functionalized surface on which the initiation sites for polymerization are spaced at distances consistent with the helical diameter of the peptide. Completely helical polyalanine and polyphenylalanine layers have been constructed. The helicity of the polyalanine layer was completely retained after heating at 180-degrees-C for 7 days.

引用

收藏

页码：73 / 76

页数：4

相关论文

共 19 条

[1] IMPROVED 2ND-HARMONIC GENERATION FROM LANGMUIR-BLODGETT-FILMS OF HEMICYANINE DYES [J].

ASHWELL, GJ ;

HARGREAVES, RC ;

BALDWIN, CE ;

BAHRA, GS ;

BROWN, CR .

NATURE, 1992, 357 (6377) :393-395

[2] 2ND-HARMONIC GENERATION IN POLY(ALPHA-AMINO ACID) AND POLY(ISOCYANATE) FILMS [J].

BLOCK, H ;

SHAW, CP .

POLYMER, 1992, 33 (11) :2459-2462

[3]

Chemla D. S., 1987, NONLINEAR OPTICAL PR, V1

[4]

Chemla D.S., 1987, NONLINEAR OPTICAL PR, V2

[5] FULLERENE SELF-ASSEMBLY ONTO (MEO)3SI(CH2)3NH2-MODIFIED OXIDE SURFACES [J].

CHEN, KM ;

CALDWELL, WB ;

MIRKIN, CA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (03) :1193-1194

[6] VOLTAMMETRIC AND ELECTROCHROMIC BEHAVIOR OF N-HEPTYLVIOLOGEN ON CHEMICALLY MODIFIED METAL-OXIDE ELECTRODES [J].

CIESLINSKI, RC ;

ARMSTRONG, NR .

JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 1980, 127 (12) :2605-2610

[7] NONLINEAR OPTICAL-MATERIALS [J].

EATON, DF .

SCIENCE, 1991, 253 (5017) :281-287

[8] OMEGA-TERMINATED ALKANETHIOLATE MONOLAYERS ON SURFACES OF COPPER, SILVER, AND GOLD HAVE SIMILAR WETTABILITIES [J].

LAIBINIS, PE ;

WHITESIDES, GM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (06) :1990-1995

[9] 2ND ORDER HYPERPOLARIZABILITY OF A POLYPEPTIDE ALPHA-HELIX - POLY-GAMMA-BENZYL-L-GLUTAMATE [J].

LEVINE, BF ;

BETHEA, CG .

JOURNAL OF CHEMICAL PHYSICS, 1976, 65 (05) :1989-1993

[10] INTERNAL STARK-EFFECT MEASUREMENT OF THE ELECTRIC-FIELD AT THE AMINO TERMINUS OF AN ALPHA-HELIX [J].

LOCKHART, DJ ;

KIM, PS .

SCIENCE, 1992, 257 (5072) :947-951