RECEPTOR TYROSINE KINASES - GENETIC-EVIDENCE FOR THEIR ROLE IN DROSOPHILA AND MOUSE DEVELOPMENT

被引：170

作者：

PAWSON, T

BERNSTEIN, A

机构：

[1] T. Pawson and A. Bernstein are in the Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ont. M5G 1X5

来源：

TRENDS IN GENETICS | 1990年 / 6卷 / 11期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0168-9525(90)90276-C

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Receptor tyrosine kinases (RTKs) and their ligands are important components of the signalling pathways by which cells interact. This review summarizes a growing body of genetic evidence showing that many developmentally important mutations in Drosophila and the mouse are in the genes that encode RTKs or their ligands, indicating that these molecules play central roles during both invertebrate and vertebrate development. © 1990.

引用

页码：350 / 356

页数：7

共 39 条

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