THE INTRACELLULAR-DISTRIBUTION AND ACTIVITIES OF PHOSPHOENOLPYRUVATE CARBOXYKINASE ISOZYMES IN VARIOUS TISSUES OF SEVERAL MAMMALS AND BIRDS

被引：38

作者：

WIESE, TJ ^{[1
]}

LAMBETH, DO ^{[1
]}

RAY, PD ^{[1
]}

机构：

[1] UNIV N DAKOTA,SCH MED,DEPT BIOCHEM & MOLEC BIOL,GRAND FORKS,ND 58202

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1991年 / 100卷 / 02期

关键词：

D O I：

10.1016/0305-0491(91)90378-Q

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. The intracellular distribution and/or activities of phosphoenolpyruvate carboxykinase isozymes were determined in liver, kidney, gastrointestinal mucosa, adipose, skeletal muscle, brain, spleen, lung and heart of fed and fasted rabbits, guinea pigs, rats, chickens and pigeons. 2. Liver and kidney of all species contained the highest enzyme activity/g. 3. Carboxykinase activity/g gastrointestinal mucosa of rabbits was quite high compared to the low activity in guinea pig and rat mucosa and essentially undetectable activity in chicken and pigeon mucosa. 4. Activity/g was high in rat brown adipose. 5. Low carboxykinase activity/g was found in skeletal muscle of all species and in white adipose of guinea pig, rabbit and rat although activity was undetectable in white adipose of chicken and pigeon. 6. Carboxykinase activity was essentially undetectable in brain, spleen, lung and heart of all species.

引用

页码：297 / 302

页数：6

共 50 条

[1] PYRUVATE CARBOXYLASE AND PHOSPHOENOLPYRUVATE CARBOXYKINASE IN RAT INTESTINAL MUCOSA [J].

ANDERSON, JW .

BIOCHIMICA ET BIOPHYSICA ACTA, 1970, 208 (01) :165-&

[2]

BALLARD FJ, 1967, J BIOL CHEM, V242, P2746

[3]

BALLARD FJ, 1969, J BIOL CHEM, V244, P5625

[4]

CARLSEN BD, 1988, BIOCHIM BIOPHYS ACTA, V965, P1

[5] GLYCEROKINASE IN MUCOSA OF SMALL INTESTINE OF CAT [J].

CLARK, B ;

HUBSCHER, G .

NATURE, 1962, 195 (4841) :599-&

[6] HUMAN LIVER PHOSPHOENOLPYRUVATE CARBOXYKINASE - EVIDENCE FOR A SEPARATE MITOCHONDRIAL AND CYTOSOL ENZYME [J].

DIESTERHAFT, M ;

SHRAGO, E ;

SALLACH, HJ .

BIOCHEMICAL MEDICINE, 1971, 5 (04) :297-+

[7] 3-MERCAPTOPICOLINIC ACID, AN INHIBITOR OF GLUCONEOGENESIS [J].

DITULLIO, NW ;

BERKOFF, CE ;

BLANK, B ;

KOSTOS, V ;

STACK, EJ ;

SAUNDERS, HL .

BIOCHEMICAL JOURNAL, 1974, 138 (03) :387-394

[8] EVIDENCE FOR LACTATE UTILIZATION FOR FETAL LUNG GLYCOGEN-SYNTHESIS [J].

ENGLE, MJ ;

DOOLEY, M ;

BROWN, DJ .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 145 (01) :397-401

[9] PHOSPHOENOLPYRUVATE CARBOXYKINASE OF KIDNEY - SUBCELLULAR DISTRIBUTION AND RESPONSE TO ACID-BASE CHANGES [J].

FLORES, H ;

ALLEYNE, GAO .

BIOCHEMICAL JOURNAL, 1971, 123 (01) :35-&

[10] STUDIES ON MECHANISMS UNDERLYING ADAPTIVE CHANGES IN RAT LIVER PHOSPHOENOLPYRUVATE CARBOXYKINASE [J].

FOSTER, DO ;

RAY, PD ;

LARDY, HA .

BIOCHEMISTRY, 1966, 5 (02) :555-&

← 1 2 3 4 5 →