IMMUNITY AND DEPRESSION - INSOMNIA, RETARDATION, AND REDUCTION OF NATURAL-KILLER-CELL ACTIVITY

被引：67

作者：

COVER, H

IRWIN, M

机构：

[1] VET AFFAIRS MED CTR,DEPT PSYCHIAT,9116-A,3350 LA JOLLA VILLAGE DR,SAN DIEGO,CA 92161

[2] UNIV CALIF SAN DIEGO,DEPT PSYCHIAT,SAN DIEGO,CA 92103

来源：

JOURNAL OF BEHAVIORAL MEDICINE | 1994年 / 17卷 / 02期

关键词：

PSYCHONEUROIMMUNOLOGY; DEPRESSION; IMMUNITY; INSOMNIA; NATURAL KILLER CELL ACTIVITY;

D O I：

10.1007/BF01858106

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Depressed patients show a reduction of natural killer (NK) cell activity which may be associated with specific depressive symptoms. The present study demonstrated that sleep disturbance and retardation, but not other depressive symptoms, were negatively correlated with NK activity in 38 depressed patients. Specific behavioral changes in depression such as sleep disturbance and retardation were found to predict 16% of the variance of cytotoxicity levels in depression.

引用

页码：217 / 223

页数：7

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