SILICON RIBBON CABLES FOR CHRONICALLY IMPLANTABLE MICROELECTRODE ARRAYS

被引:116
作者
HETKE, JF
LUND, JL
NAJAFI, K
WISE, KD
ANDERSON, DJ
机构
[1] Center for Integrated Sensors and Circuits, Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor
关键词
D O I
10.1109/10.284959
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This paper describes the design, fabrication, and testing of miniature ultraflexible ribbon cables for use with micromachined silicon microprobes capable of chronic recording and/or stimulation in the central nervous system (CNS). These interconnects are of critical importance in reliably linking these microelectrodes to the external world through a percutaneous connector. The silicon cables allow the realization of multilead, multistrand shielded local interconnects that are extremely flexible and yet strong enough to withstand normal handling and surgical manipulation. Cables 5 mu m thick, 1-5 cm long, and from 60 to 250 mu m wide have been fabricated with up to eight leads. The series lead resistance is typically 4 k Omega/cm for polysilicon and 500 Omega/cm for tantalum, with shunt capacitance values of 5-10 pF/cm and an interlead capacitance below 10 fF/cm. Soak tests in buffered saline performed under electrical and mechanical stress have been underway for over three years and show subpicoampere leakage levels. Silicon microprobes with built-in ribbon cables have remained functional for up to one year in the guinea pig CNS, recording driven single-unit activity and maintaining impedance levels in the 1-7 M Omega range.
引用
收藏
页码:314 / 321
页数:8
相关论文
共 21 条
  • [1] ANDERSON DJ, 1989, IEEE T BIOMED ENG, V36, P673
  • [2] HIGH-FREQUENCY NETWORK OSCILLATION IN THE HIPPOCAMPUS
    BUZSAKI, G
    HORVATH, Z
    URIOSTE, R
    HETKE, J
    WISE, K
    [J]. SCIENCE, 1992, 256 (5059) : 1025 - 1027
  • [3] DELGADO JMR, 1964, PHYSICAL TECHNIQUES
  • [4] DEMENT SL, 1986, IEEE T BIOMED ENG, V33, P230
  • [5] PERFORMANCE OF PLANAR MULTISITE MICROPROBES IN RECORDING EXTRACELLULAR SINGLE-UNIT INTRACORTICAL ACTIVITY
    DRAKE, KL
    WISE, KD
    FARRAYE, J
    ANDERSON, DJ
    BEMENT, SL
    [J]. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1988, 35 (09) : 719 - 732
  • [6] NEURAL INTERACTION IN CAT PRIMARY AUDITORY-CORTEX - DEPENDENCE ON RECORDING DEPTH, ELECTRODE SEPARATION, AND AGE
    EGGERMONT, JJ
    [J]. JOURNAL OF NEUROPHYSIOLOGY, 1992, 68 (04) : 1216 - 1228
  • [7] HETKE JF, 1991, TRANSDUCERS 91 INT C
  • [8] HETKE JF, 1990, SENSOR ACTUAT A-PHYS, V21, P999
  • [9] AN IMPLANTABLE CMOS CIRCUIT INTERFACE FOR MULTIPLEXED MICROELECTRODE RECORDING ARRAYS
    JI, J
    WISE, KD
    [J]. IEEE JOURNAL OF SOLID-STATE CIRCUITS, 1992, 27 (03) : 433 - 443
  • [10] KRUGER J, 1981, EXP BRAIN RES, V41, P191