MAMMARY-GLAND EXPRESSION OF TRANSGENES AND THE POTENTIAL FOR ALTERING THE PROPERTIES OF MILK

被引：82

作者：

MAGA, EA ^{[1
]}

MURRAY, JD ^{[1
]}

机构：

[1] UNIV CALIF DAVIS, SCH VET MED, DEPT POPULAT HLTH & REPROD, DAVIS, CA 95616 USA

来源：

BIO-TECHNOLOGY | 1995年 / 13卷 / 13期

关键词：

D O I：

10.1038/nbt1295-1452

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Transgenic animals are a useful in vivo experimental model for assessing the ability and impact of foreign gene expression in a biological system. Transgenic mice are most commonly used, while transgenic sheep, goats, pigs and cows have also been developed for specific, ''applied'' purposes. Most of the work directed at targeting expression of transgenes to the mammary gland of an animal, by using a milk gene promoter, has been with the intent of either studying promoter function or recovering the desired protein from the milk. Transgenic technology can also be used to alter the functional and physical properties of milk resulting in novel manufacturing properties. The properties of milk have been altered by adding a new protein with the aim of improving the milk, not of recovering the protein for other uses.

引用

页码：1452 / 1457

页数：6

共 110 条

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