HEMAGGLUTININ AND HEMOLYSIN LEVELS IN THE CELOMIC FLUID FROM HOLOTHURIA-POLII (ECHINODERMATA) FOLLOWING SHEEP ERYTHROCYTE INJECTION

After injection of formalinized sheep erythrocytes into the coelomic cavity of H. polii the activity of the naturally occurring hemagglutinins remained constant; the hemolysin level rose over 8 days. The kinetics of the responses were the same after a further injection, although the hemolytic titers reached higher levels over a longer period. Results obtained using rabbit erythrocytes indicate that this response can be considered a secondary one: higher titers were demonstrated over 24 h. Properties of naturally occurring and induced hemolysins are discussed.