SYNTHESIS AND BIOLOGICAL EVALUATION OF 3-AMINO-2-(4-CHLOROPHENYL) 1,1-DIFLUOROPROPYL PHOSPHONIC ACID

被引：21

作者：

HOWSON, W ^{[1
]}

HILLS, JM ^{[1
]}

BLACKBURN, GM ^{[1
]}

BROEKMAN, M ^{[1
]}

机构：

[1] SHEFFIELD UNIV,DEPT CHEM,SHEFFIELD S3 7HF,ENGLAND

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1991年 / 1卷 / 10期

关键词：

D O I：

10.1016/S0960-894X(01)80452-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The synthesis of the alpha-difluoro analogue (1) of the GABA(B) antagonist phaclofen (2) is described along with its action on a GABA(B) functional assay.

引用

页码：501 / 502

页数：2

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