ROTATIONAL-ISOMERISM IN 5-AMINO-6-(N-METHYLFORMAMIDO)-AS-TRIAZIN-3(2H)-ONE

被引：5

作者：

RIAND, J

TANGUY, M

CHENON, MT

TZENG, CC

PANZICA, RP

机构：

[1] CNRS,LASIR,2 RUE HENRI DUNANT,F-94320 THIAIS,FRANCE

[2] UNIV RHODE ISL,DEPT MED CHEM,KINGSTON,RI 02881

[3] UNIV RHODE ISL,DEPT CHEM,KINGSTON,RI 02881

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 1990年 / 28卷 / 06期

关键词：

!sup]1[!/sup]H DNMR; 6‐Azapurin‐2‐ones; 6‐Azapyrimidin‐2‐ones; Rotational isomerism;

D O I：

10.1002/mrc.1260280607

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A 1H dynamic NMR study of the hindered rotation in 5‐amino‐6‐(N‐methylformamido)‐as‐triazin‐3(2H)‐one was conducted. Signals for two rotamers were observed and their proton chemical shifts were assigned. It was found that the rotamer in which the as‐triazine ring is cis to the formyl hydrogen predominates. The free energies of activation for hindered rotations about the N CHO and C NH2 bonds were determined by 1H NMR line‐shape analysis. Copyright © 1990 John Wiley & Sons, Ltd.

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页码：505 / 509

页数：5

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