ARE CONVENTIONAL RISK-FACTORS FOR MORTALITY RELEVANT IN TYPE-2 DIABETES

被引：39

作者：

FITZGERALD, AP ^{[1
]}

JARRETT, RJ ^{[1
]}

机构：

[1] UNITED MED & DENT SCH GUYS & ST THOMASS HOSP,DEPT PUBL HLTH MED,GUYS CAMPUS,LONDON SE1 9RT,ENGLAND

来源：

DIABETIC MEDICINE | 1991年 / 8卷 / 05期

关键词：

TYPE-2; DIABETES; MORTALITY; ISCHEMIC HEART DISEASE; RISK FACTORS;

D O I：

10.1111/j.1464-5491.1991.tb01635.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

One-hundred and ninety-one men with Type 2 (non-insulin-dependent) diabetes mellitus, participants in the Whitehall Survey, were followed for 15 years. Age-adjusted all-cause and ischaemic heart disease (IHD) mortality rates were significantly increased in the diabetic men. Of four putative risk factors for IHD ascertained in the survey (plasma cholesterol, systolic blood pressure, cigarette smoking, body mass index) only blood pressure was a significant predictor in univariate Cox regression analysis. A review of comparable studies revealed lack of consistency in the association of these risk factors (derived from studies in non-diabetic populations) and mortality in individuals with Type 2 diabetes. Given the absence of clinical trial data, risk factor intervention in Type 2 diabetes is currently based upon inference derived from studies in non-diabetic subjects.

引用

页码：475 / 480

页数：6

共 31 条

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