IMPROVED MICROSCOPIC DIAGNOSIS OF PULMONARY TUBERCULOSIS IN DEVELOPING-COUNTRIES

被引：69

作者：

GEBRE, N

KARLSSON, U

JONSSON, G

MACADEN, R

WOLDE, A

ASSEFA, A

MIORNER, H

机构：

[1] ARMAUER HANSEN RES INST, ADDIS ABABA, ETHIOPIA

[2] LUND UNIV, DEPT MED MICROBIOL, LUND, SWEDEN

[3] ST JOHNS MED COLL, BANGALORE, KARNATAKA, INDIA

[4] ADDIS ABABA TB DEMONSTRAT & TRAINING CTR, ADDIS ABABA, ETHIOPIA

[5] GONDAR COLL MED SCI, Gondar, ETHIOPIA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1995年 / 89卷 / 02期

关键词：

TUBERCULOSIS; DIAGNOSIS BY MICROSCOPY;

D O I：

10.1016/0035-9203(95)90491-3

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The diagnosis of pulmonary tuberculosis (TB) relies on the bacteriological examination of sputum. However, microscopy of smears made directly from sputum has a low sensitivity and there is an urgent need for improved methods. We have compared microscopy of smears made directly from sputum with microscopy after liquefaction of sputum with household bleach (NaOCl) and concentration of bacteria by centrifugation. In 3 studies performed in Ethiopia and India, the use of the NaOCl method increased the number of samples positive for acid-fast bacilli by more than 100%. The technique is appropriate for developing countries and its application would increase the efficiency of TB control programmes. As a potent disinfectant, NaOCl also has the advantage of lowering the risk of laboratory infection.

引用

页码：191 / 193

页数：3

共 15 条

[1] QUALITY-CONTROL IN TUBERCULOSIS BACTERIOLOGY .1. LABORATORY STUDIES ON ISOLATED POSITIVE CULTURES AND THE EFFICIENCY OF DIRECT SMEAR EXAMINATION [J].