STRUCTURAL ASPECTS OF ALLORECOGNITION

被引：33

作者：

LECHLER, R

LOMBARDI, G

机构：

[1] Department of Immunology, Royal Postgraduate Medical School, London, W12 ONN, Du Cane Road

来源：

CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 05期

关键词：

D O I：

10.1016/0952-7915(91)90102-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The phenomenon of T-cell allorecognition of foreign major histocompatibility molecules has been one of the more enigmatic aspects of T-cell immunology. The molecular basis for allorecognition is unfolding as a result of the application of major histocompatibility complex structure/function analyses in the light of current insights into the three-dimensional structure of major histocompatibility complex products.

引用

收藏

页码：715 / 721

页数：7

相关论文

共 41 条

[1] EVIDENCE THAT MULTIPLE RESIDUES ON BOTH THE ALPHA-HELICES OF THE CLASS-I MHC MOLECULE ARE SIMULTANEOUSLY RECOGNIZED BY THE T-CELL RECEPTOR [J].

AJITKUMAR, P ;

GEIER, SS ;

KESARI, KV ;

BORRIELLO, F ;

NAKAGAWA, M ;

BLUESTONE, JA ;

SAPER, MA ;

WILEY, DC ;

NATHENSON, SG .

CELL, 1988, 54 (01) :47-56

[2] STRUCTURE OF THE HUMAN CLASS-I HISTOCOMPATIBILITY ANTIGEN, HLA-A2 [J].

BJORKMAN, PJ ;

SAPER, MA ;

SAMRAOUI, B ;

BENNETT, WS ;

STROMINGER, JL ;

WILEY, DC .

NATURE, 1987, 329 (6139) :506-512

[3] A HYPOTHETICAL MODEL OF THE FOREIGN ANTIGEN-BINDING SITE OF CLASS-II HISTOCOMPATIBILITY MOLECULES [J].

BROWN, JH ;

JARDETZKY, T ;

SAPER, MA ;

SAMRAOUI, B ;

BJORKMAN, PJ ;

WILEY, DC .

NATURE, 1988, 332 (6167) :845-850

[4]

CLAYBERGER C, 1990, J IMMUNOL, V144, P4172

[5]

COTNER T, 1990, J IMMUNOL, V146, P414

[6] T-CELL ANTIGEN RECEPTOR GENES AND T-CELL RECOGNITION [J].

DAVIS, MM ;

BJORKMAN, PJ .

NATURE, 1988, 334 (6181) :395-402

[7] A SINGLE AMINO-ACID SUBSTITUTION IN THE AK MOLECULE FORTUITOUSLY PROVOKES AN ALLORESPONSE [J].

DELLABONA, P ;

WEI, BY ;

GERVOIS, N ;

BENOIST, C ;

MATHIS, D .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1991, 21 (01) :209-213

[8] PEPTIDE-MEDIATED MODULATION OF T-CELL ALLORECOGNITION [J].

ECKELS, DD ;

GORSKI, J ;

ROTHBARD, J ;

LAMB, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (21) :8191-8195

[9] CYTOTOXIC LYMPHOCYTES-T RECOGNIZE A RECONSTITUTED CLASS-I HISTOCOMPATIBILITY ANTIGEN (HLA-A2) AS AN ALLOGENEIC TARGET MOLECULE [J].

ELLIOTT, TJ ;

EISEN, HN .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (13) :5213-5217

[10] CORECOGNITION OF HLA-A1 AND HLA-DPW3 BY A HUMAN CD4+ ALLOREACTIVE LYMPHOCYTE-T CLONE [J].

ESSAKET, S ;

FABRON, J ;

DEPREVAL, C ;

THOMSEN, M .

JOURNAL OF EXPERIMENTAL MEDICINE, 1990, 172 (01) :387-390

← 1 2 3 4 5 →