ERYTHROPOIETIC SUPPRESSION IN FETAL ANEMIA BECAUSE OF KELL ALLOIMMUNIZATION

被引:106
作者
VAUGHAN, JI
WARWICK, R
LETSKY, E
NICOLINI, U
RODECK, CH
FISK, NM
机构
[1] Royal Postgraduate Medical School, Institute of Obstetrics and Gynaecology, Queen Charlotte's and Chelsea Hospital, London
关键词
KELL ALLOIMMUNIZATION; FETAL ANEMIA; RETICULOCYTOSIS; LILEYS CHARTS;
D O I
10.1016/0002-9378(94)90477-4
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
OBJECTIVE: Our purpose was to test the hypothesis that maternal anti-Kell alloimmunization produces fetal anemia by erythroid suppression. STUDY DESIGN: Erythropoiesis in 11 anemic fetuses from maternal anti-Kell alloimmunization was compared with that in 11 fetuses where the mother was alloimmunized to RhD; each was matched for hematocrit, gestational age, hydrops, and perinatal outcome. Comparisons of the difference were performed by either paired t or Wilcoxon tests.
引用
收藏
页码:247 / 252
页数:6
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