CHIRAL SEPARATION BY CAPILLARY ELECTROPHORESIS WITH OLIGOSACCHARIDES

被引：141

作者：

DHULST, A ^{[1
]}

VERBEKE, N ^{[1
]}

机构：

[1] CATHOLIC UNIV LEUVEN,PHARM CLIN,HERESTR 49,B-3000 LOUVAIN,BELGIUM

来源：

JOURNAL OF CHROMATOGRAPHY | 1992年 / 608卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(92)87134-T

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Maltodextrins, i.e., mixtures of linear alpha-(1-4)-linked D-glucose polymers, were found to be effective as chiral electrolyte modifiers to perform direct, rapid separations by capillary electrophoresis of racemic mixtures of 2-arylpropionic acid non-steroidal anti-inflammatory compounds and coumarinic anticoagulant drugs, and also diastereomeric cefalosporin antibiotics. Enantioselectivity seemed to be dependent on an as yet unidentified combination of variables.

引用

页码：275 / 287

页数：13

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