ISOELECTRIC RESTRICTION OF HUMAN-IMMUNOGLOBULIN ISOTYPES

被引：56

作者：

PRIN, C

BENE, MC

GOBERT, B

MONTAGNE, P

FAURE, GC

机构：

[1] Laboratoire d'Immunologie, Faculté de Médecine de Nancy, 54500 Vandoeuvre Les Nancy

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS | 1995年 / 1243卷 / 02期

关键词：

IMMUNOGLOBULIN; IGA; IGG; IGM; ISOELECTRIC FOCUSING; (HUMAN);

D O I：

10.1016/0304-4165(94)00187-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The partition of human serum immunoglobulins along a pH gradient of ampholynes was investigated using the recently developed method of preparative isoelectrofocusing. Each isotype was demonstrated to display a specific pi range, with limited overlapping. IgA appear to be the most acidic serum immunoglobulins while IgG are clearly basic.

引用

页码：287 / 289

页数：3

共 8 条

[1] ISOELECTRIC-FOCUSING OF HUMAN-IGA AND SECRETORY PROTEINS USING THIN-LAYER AGAROSE GELS AND NITROCELLULOSE CAPILLARY BLOTTING [J].