PREDOMINANCE OF NORMAL KARYOTYPE IN COLORECTAL TUMORS FROM HEREDITARY NONPOLYPOSIS COLORECTAL-CANCER PATIENTS

被引：28

作者：

MULERIS, M

DUTRILLAUX, AM

OLSCHWANG, S

SALMON, RJ

DUTRILLAUX, B

机构：

[1] INST CURIE,GENET TUMEURS LAB,PARIS,FRANCE

[2] INST CURIE,DEPT MED,PARIS,FRANCE

来源：

GENES CHROMOSOMES & CANCER | 1995年 / 14卷 / 03期

关键词：

D O I：

10.1002/gcc.2870140312

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report the cytogenetic study of 9 colorectal tumors arising in patients with hereditary non-polyposis colorectal cancer (HNPCC). According to the cytogenetic classification of colorectal tumors previously proposed by us, 2 cases were of the trisomic type, 2 were of the monosomic type, and 5 had a normal karyotype. This represents a significant excess of tumors with normal karyotype in HNPCC tumors (56%) compared to sporadic cases (10/184 = 5%). (C) 1995 Wiley-Liss, Inc.

引用

页码：223 / 226

页数：4

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