MAPPING OF THE 19P13 BREAKPOINT IN AN OVARIAN-CARCINOMA BETWEEN THE INSR AND TCF3 LOCI

被引：8

作者：

AMAN, P

PEJOVIC, T

WENNBORG, A

HEIM, S

MITELMAN, F

机构：

[1] KAROLINSKA INST,DEPT TUMOR BIOL,S-10401 STOCKHOLM 60,SWEDEN

[2] ODENSE UNIV,DEPT MED GENET,DK-5230 ODENSE,DENMARK

来源：

GENES CHROMOSOMES & CANCER | 1993年 / 8卷 / 02期

关键词：

D O I：

10.1002/gcc.2870080212

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Chromosome rearrangements involving band 19p13 have been described in about half of all ovarian carcinomas. Four ovarian carcinomas with translocations of 19p13 were investigated with 11 DNA probes for markers localized to this band. All markers exhibited normal restriction patterns, suggesting that they were not, rearranged. The 19p13 breakpoint of one tumor was mapped to a location between the INSR and the TCF3 loci. (C) 1993 Wiley-Liss, Inc.

引用

页码：134 / 136

页数：3

共 21 条

[1] AN ECORI POLYMORPHISM AT THE INSULIN-RECEPTOR LOCUS ON A FRAGMENT COMPRISING EXON-4 TO EXON-8 [J].