THE GENOME OF CAENORHABDITIS-ELEGANS

被引：112

作者：

WATERSTON, R ^{[1
]}

SULSTON, J ^{[1
]}

机构：

[1] WASHINGTON UNIV,SCH MED,CTR GENOME SEQUENCING,ST LOUIS,MO 63110

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1995年 / 92卷 / 24期

关键词：

D O I：

10.1073/pnas.92.24.10836

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The physical map of the 100-Mb Caenorhabditis elegans genome consists of 17,500 cosmids and 3500 yeast artificial chromosomes (YACs). A total of 22.5 Mb has been sequenced, with the remainder expected by 1998. A further 15.5 Mb of unfinished sequence is freely available online: because the areas sequenced so far are relatively gene rich, about half the 13,000 genes can now be scanned. More than a quarter of the genes are represented by expressed sequence tags (ESTs), All information pertaining to the genome is publicly available in the ACeDB data base.

引用

页码：10836 / 10840

页数：5

共 23 条

[1] MAPPING MUSCLE PROTEIN GENES BY INSITU HYBRIDIZATION USING BIOTIN-LABELED PROBES
ALBERTSON, DG
[J]. EMBO JOURNAL, 1985, 4 (10) : 2493 - 2498
[2] BASIC LOCAL ALIGNMENT SEARCH TOOL
ALTSCHUL, SF
GISH, W
MILLER, W
MYERS, EW
LIPMAN, DJ
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1990, 215 (03) : 403 - 410
[3] TOWARD A PHYSICAL MAP OF THE GENOME OF THE NEMATODE CAENORHABDITIS-ELEGANS
COULSON, A
SULSTON, J
BRENNER, S
KARN, J
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (20) : 7821 - 7825
[4] GENOME LINKING WITH YEAST ARTIFICIAL CHROMOSOMES
COULSON, A
WATERSTON, R
KIFF, J
SULSTON, J
KOHARA, Y
[J]. NATURE, 1988, 335 (6186) : 184 - 186
[5] YACS AND THE C-ELEGANS GENOME
COULSON, A
KOZONO, Y
LUTTERBACH, B
SHOWNKEEN, R
SULSTON, J
WATERSTON, R
[J]. BIOESSAYS, 1991, 13 (08) : 413 - 417
[6] DURBIN R, 1994, COMPUTATIONAL METHOD
[7] EDGLEY ML, 1990, GENETIC MAPS, V5, P3
[8] HOPE IA, 1994, DEVELOPMENT, V120, P505
[9] HOWELL AM, 1990, GENETICS, V126, P583
[10] IOANNOU PA, 1994, NAT GENET, V6, P84, DOI 10.1038/ng0194-84

← 1 2 3 →