BIOCATALYTICAL TRANSFORMATIONS .6. THE 4-ACETAMIDO-CYCLOPENT-2-ENE CARBOXYLATE ROUTE REVISITED - SYNTHESIS OF (+)-ARISTEROMYCIN AND (-)-ARISTEROMYCIN

被引：17

作者：

CSUK, R

DORR, P

机构：

[1] Pharmazeutisch-Chemisches Institut, Universität Heidelberg, D-69120 Heidelberg

来源：

TETRAHEDRON | 1995年 / 51卷 / 20期

关键词：

D O I：

10.1016/0040-4020(95)00246-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantiomerically pure (+)- as well as (-)-aristeromycin can be synthesized starting from (+)- or (-)-butyl (or hexyl) 4-acetamido-cyclopent-2-ene carboxylate; these carboxylates are easily obtained from their corresponding racemates by hydrolysis with the lipase from Candida rugosa.

引用

页码：5789 / 5798

页数：10

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