TRIMERIC C-TYPE LECTIN DOMAINS IN HOST-DEFENSE - RECENT CRYSTAL-STRUCTURES, ESTABLISHED FOR FRAGMENTS OF HUMAN AND RAT MANNOSE-BINDING PROTEINS, INDICATE THAT THE TRIPLE-STRANDED ALPHA-HELICAL COILED-COIL PRESENT IN THESE COLLECTINS IS RESPONSIBLE FOR THE TRIMERIC ORIENTATION OF C-TYPE LECTIN DOMAINS

被引：41

作者：

HOPPE, HJ

REID, KBM

机构：

来源：

STRUCTURE | 1994年 / 2卷 / 12期

关键词：

D O I：

10.1016/S0969-2126(94)00115-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent crystal structures, established for fragments of human and rat mannose-binding proteins, indicate that the triple-stranded alpha-helical coiled coil present in these collectins is responsible for the trimeric orientation of C-type lectin domains.

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页码：1129 / 1133

页数：5

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