IMMUNOSUPPRESSIVE ACTIVITY OF SERA OF PREGNANT-WOMEN AN CYTOTOXIC T-LYMPHOCYTE-MEDIATED CYTOLYSIS .1. CHARACTERIZATION OF THE ACTIVE FRACTION

被引：4

作者：

LETELLIER, C ^{[1
]}

FIZET, D ^{[1
]}

BALTZ, T ^{[1
]}

VEZON, G ^{[1
]}

机构：

[1] UNIV BORDEAUX 2,IMMUNOL & BIOL MOLEC PARASITES LAB,BORDEAUX,FRANCE

来源：

GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 1994年 / 37卷 / 01期

关键词：

IMMUNOLOGY; HUMAN PREGNANCY; IMMUNOSUPPRESSIVE ACTIVITY; CYTOTOXIC T LYMPHOCYTES; CELL-MEDIATED LYMPHOLYSIS ASSAY;

D O I：

10.1159/000292509

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Sera of healthy pregnant women have a nonspecific inhibitory activity on the specific cytolytic activity of activated cytotoxic T lymphocytes in vitro. The serum fraction of pregnant females which is responsible for this activity has been characterized. The equivalent fraction derived from sera of healthy men has a similar but reduced activity compared with the female fraction. This suppressive factor seems to be activated during pregnancy. Moreover, this study sheds some light an the reasons behind the attenuation of the maternal immune system during pregnancy.

引用

页码：1 / 5

页数：5

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