VALPROIC ACID TERATOGENICITY - DEMONSTRATION THAT THE BIOCHEMICAL-MECHANISM DIFFERS FROM THAT OF VALPROATE HEPATOTOXICITY

被引：20

作者：

BROWN, NA ^{[1
]}

FARMER, PB ^{[1
]}

COAKLEY, M ^{[1
]}

机构：

[1] MRC LABS,MRC,TOXICOL UNIT,CARSHALTON SM5 4EF,SURREY,ENGLAND

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 1985年 / 13卷 / 01期

关键词：

D O I：

10.1042/bst0130075

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：75 / 77

页数：3

共 12 条

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[2]

BROWN NA, 1980, LANCET, V1, P660

[3]

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[4] TERATOGENIC EFFECTS OF VALPROIC ACID AND DIPHENYLHYDANTOIN ON MOUSE EMBRYOS IN CULTURE [J].

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LEE, YJ ;

OSHEA, KS ;

HENNEBERRY, RC .

TERATOLOGY, 1983, 27 (01) :29-42

[5] INHIBITION OF UREAGENESIS BY VALPROATE IN RAT HEPATOCYTES - ROLE OF N-ACETYLGLUTAMATE AND ACETYL-COA [J].

COUDE, FX ;

GRIMBER, G ;

PARVY, P ;

RABIER, D ;

PETIT, F .

BIOCHEMICAL JOURNAL, 1983, 216 (01) :233-236

[6] ACTION OF THE ANTI-EPILEPTIC DRUG, VALPROIC ACID, ON FATTY-ACID OXIDATION IN ISOLATED RAT HEPATOCYTES [J].

COUDE, FX ;

GRIMBER, G ;

PELET, A ;

BENOIT, Y .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 115 (02) :730-736

[7]

Editorial, 1982, LANCET, Vii, P1313

[8]

KAO J, 1981, Teratogenesis Carcinogenesis and Mutagenesis, V1, P367, DOI 10.1002/tcm.1770010405

[9] TERATOGENESIS OF CALCIUM VALPROATE IN RATS [J].

ONG, LL ;

SCHARDEIN, JL ;

PETRERE, JA ;

SAKOWSKI, R ;

JORDAN, H ;

HUMPHREY, RR ;

FITZGERALD, JE ;

DELAIGLESIA, FA .

FUNDAMENTAL AND APPLIED TOXICOLOGY, 1983, 3 (02) :121-126

[10]

PANDE SV, 1981, ANAL BIOCH, V11, P30

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