ARGYROPHILIC THREAD-LIKE STRUCTURE IN CORTICOBASAL DEGENERATION AND SUPRANUCLEAR PALSY

被引：92

作者：

IKEDA, K

AKIYAMA, H

HAGA, C

KONDO, H

ARIMA, K

ODA, T

机构：

[1] NATL CTR HOSP MENT NERVOUS & MUSCULAR DISORDERS,DEPT PSYCHIAT,KODAIRA 187,TOKYO,JAPAN

[2] NATL SHIMOFUSA SANATORIUM,DEPT PSYCHIAT,CHIBA 28002,JAPAN

来源：

NEUROSCIENCE LETTERS | 1994年 / 174卷 / 02期

关键词：

ARGYROPHILIC THREAD-LIKE STRUCTURE; OLIGODENDROGLIA; TAU PROTEIN; CORTICOBASAL DEGENERATION; PROGRESSIVE SUPRANUCLEAR PALSY;

D O I：

10.1016/0304-3940(94)90010-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Massive argyrophilic thread-like structures (ATS) are observed in corticobasal degeneration and, in varied degrees, in some cases of progressive supranuclear palsy. Immunohistochemically, ATS has a full length of phosphorylated tau epitopes without ubiquitin. Gallyas- and immune-electron microscopic observation revealed that ATS is a cytoskeletal abnormality occurred in both the inner and outer loop of the oligodendroglia. tau-Positive oligodendroglial tangles were distributed in the same region as ATS.

引用

页码：157 / 159

页数：3

共 7 条

[1] SILVER IMPREGNATION OF ALZHEIMER NEUROFIBRILLARY CHANGES COUNTERSTAINED FOR BASOPHILIC MATERIAL AND LIPOFUSCIN PIGMENT [J].