EFFECT OF AGING ON GLYCOGEN-SYNTHESIS IN LIVER OF STARVED-REFED RATS

被引：11

作者：

MYSLIWSKI, A

KMIEC, Z

机构：

[1] Department of Histology, Medical School

来源：

ARCHIVES OF GERONTOLOGY AND GERIATRICS | 1992年 / 14卷 / 01期

关键词：

STARVATION; REFEEDING; GLYCOGEN SYNTHESIS; LIVER; AGING;

D O I：

10.1016/0167-4943(92)90009-S

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 [法学]; 0303 [社会学]; 100203 [老年医学];

摘要：

Glycogen content in the livers of young, adult and old rats starved for 40 h and refed with a standard diet for 1, 2 or 4 h was determined. In the fed animals the amount of liver glycogen was similar in all the age groups. Fasting depleted liver glycogen almost completely. Chow refeeding led to glycogen synthesis in the livers of young and adult rats; however, glycogen deposition in the livers of old animals was delayed by 1 h. The amount of liver glycogen replenished in the rats refed for 4 h was similar in all the age groups. Plasma glucose concentrations were similar in all the age groups of the fed, starved and refed rats. The mechanisms of age-dependent delay of glycogen synthesis in the liver of starved-refed rats are discussed.

引用

页码：85 / 92

页数：8

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