LACTOFERRIN AS A SENSITIVE BLOOD MARKER OF NEUTROPHIL ACTIVATION IN NORMAL PREGNANCIES

被引：30

作者：

REBELO, I

CARVALHOGUERRA, F

PEREIRALEITE, L

QUINTANILHA, A

机构：

[1] UNIV PORTO, CTR CITOL EXPTL, OPORTO, PORTUGAL

[2] UNIV PORTO, HOSP S JOAO PORTO, FAC MED, DEPT OBSTET & GINECOL, OPORTO, PORTUGAL

[3] UNIV PORTO, INST CIENCIAS BIOMED ABEL SALAZAR, OPORTO, PORTUGAL

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1995年 / 62卷 / 02期

关键词：

LACTOFERRIN; PREGNANCY; NEUTROPHIL ACTIVATION;

D O I：

10.1016/0301-2115(95)02203-J

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To test lactoferrin as a marker of neutrophil activation during pregnancy. Design: Cross-sectional study in normal pregnant (n = 100), nonpregnant (n = 11) and post partum women (n = 30). Methods: Serum or plasma measurements of neutrophils, lactoferrin, vitamin C, vitamin E, lipid peroxide, elastase, C-reactive protein gamma-glulamyltranspeptidase, haptoglobin and osmotic fragility. Results: During normal pregnancy all markers of neutrophil-activation increase. Conclusion: Neutrophil-activation compromises the antioxidant defense mechanism during normal pregnancy.

引用

页码：189 / 194

页数：6

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