THE TOTAL SYNTHESIS OF RITIPENEMS - CONSTRUCTION OF PENEM THIAZOLINE RING BY INCORPORATION OF 2 2C UNITS OF GLYCOLIC ACID

被引：4

作者：

CABRI, W

ZARINI, F

DANELLO, M

MARCHI, M

BEDESCHI, A

FRANCESCHI, G

机构：

[1] Farmitalia Carlo Erba, R and D, Process Research, Via Giovanni XXIII

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(00)79192-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Short syntheses of Ritipenem Acoxyl 1a and Ritipenem 1b are reported. The syntheses start from (R)-4-acetoxy-(S)-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]azetidin-2-one 3 and are based on the incorporation of two 2C units obtained by manipulation of glicolyc acid 4.

引用

页码：3491 / 3492

页数：2

共 10 条

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