STEREOSELECTIVE ADDITION OF METHYL ACRYLATE TO ALPHA-AMINO ALDEHYDES

被引：26

作者：

MANICKUM, T ^{[1
]}

ROOS, G ^{[1
]}

机构：

[1] UNIV NATAL,DEPT CHEM,BOX 375,PIETERMARITZBURG 3200,SOUTH AFRICA

来源：

SYNTHETIC COMMUNICATIONS | 1991年 / 21卷 / 22期

关键词：

D O I：

10.1080/00397919108021585

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Variously N-protected alpha-aminoaldehydes exhibit reasonable diastereoselectivity in the Baylis-Hillman coupling 1 with methyl acrylate to provide either primarily syn or anti alpha-methylene-beta-hydroxy-gamma-amino esters.

引用

页码：2269 / 2274

页数：6

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