A REVIEW OF THE TEST METHODS USED TO ESTABLISH VIRUCIDAL ACTIVITY

被引：21

作者：

BELLAMY, K

机构：

[1] Department of Immunology, Unilever Research Laboratory, Sharnbrook, Bedfordshire MK44 1LQ, Colworth House

来源：

JOURNAL OF HOSPITAL INFECTION | 1995年 / 30卷

关键词：

DISINFECTANT EFFICACY; VIRUCIDAL ACTIVITY; ACTIVITY OF ISOPROPYL ALCOHOL;

D O I：

10.1016/0195-6701(95)90043-8

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Testing the efficacy of disinfectants has been the domain of bacteriologists for many years. Recently interest has grown in the virucidal effects of disinfectants, due to increased awareness of viral infections and concern for possible cross-infection. Findings have demonstrated significant differences in the susceptibility of certain viruses, particularly non-enveloped viruses, e.g. enteroviruses, to disinfectants compared to some bacteria. For example Escherichia coli and herpes simplex virus are inactivated by 20% isopropyl alcohol (IPA) whereas Staphylococcus aureus requires greater than or equal to 50% and poliovirus is not inactivated by IPA. Currently there is little or no standardization in the methods used for the determination of virucidal activity in suspension, or on hands and surfaces. Methods in use in Europe and the USA will be reviewed and their relevance to the clinical situation discussed.

引用

页码：389 / 396

页数：8

共 35 条

[1]

Guidelines of Bundesgesundheitsamt (BGA

[2]

German Federal Health Office) and Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten e.V. (DVV

[3]

German Association for the Control of Virus Diseases) for testing the effectiveness of chemical disinfectants against viruses, Zbl-Hyg, 189, pp. 554-562, (1990)

[4]

Antiseptiques et desinfectant utilisés a l'état liquid, miscible à l'eau, Détermination de l'activité virucide vis-à-vis des virus des vertèbres T72, 180, (1989)

[5]

Zur Prüfung der Wirkkung von chemischen Desinfektionsmitteln, Bulletin de l'office federal de la santé publique No. 25, (1985)

[6]

Water and environmental technology, E 1052-85 Annual Book of ASTM Standards, pp. 621-622, (1989)

[7]

Springthorpe, Grenier, Lloyd-Evans, Sattar, Chemical disinfection of human rotavirus: efficacy of commercially available products in suspension tests, J Hyg (Camb), 97, pp. 139-161, (1986)

[8]

Narang, Codd, Action of commonly used disinfectants against enteroviruses, J Hosp Infect, 4, pp. 209-212, (1983)

[9]

Kurtz, Lee, Parsons, The action of alcohols on rotavirus astrovirus and enterovirus, Journal of Hospital Infection, 1, pp. 321-325, (1981)

[10]

Drulak, Wallbank, Lebtag, The relative effectiveness of commonly used disinfectants in inactivation of echovirus 11, J Hyg (Camb), 81, pp. 77-87, (1978)

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