PROMOTER;
CARRIER;
DIABETES;
PHAGE-LAMBDA LIBRARY;
CLONING;
DNA SEQUENCE;
D O I:
10.1016/0378-1119(93)90438-9
中图分类号:
Q3 [遗传学];
学科分类号:
071007 ;
090102 ;
摘要:
The 5' end of a gene (GLT4) encoding a human insulin-responsive glucose transporter was isolated from a human lambdaFix genomic library and sequenced. The human sequence, as compared to the mouse GLT4 promoter [Kaestner et al., Proc. Natl. Acad. Sci. USA 87 (1990) 251-255], revealed an overall homology of 81%. Putative transcription controlling sequences were identified.