A MECHANISM OF S-(1,2,3,4,4-PENTACHLORO-1,3-BUTADIENYL)-L-CYSTEINE TOXICITY TO RABBIT RENAL PROXIMAL TUBULES

被引：45

作者：

SCHNELLMANN, RG

LOCK, EA

MANDEL, LJ

机构：

[1] ICI PLC,CENT TOXICOL LAB,BIOCHEM TOXICOL SECT,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

[2] DUKE UNIV,MED CTR,DEPT PHYSIOL,DURHAM,NC 27710

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1987年 / 90卷 / 03期

关键词：

D O I：

10.1016/0041-008X(87)90143-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：513 / 521

页数：9

共 27 条

[1] IMPROVED RENAL CORTICAL TUBULE SUSPENSION - SPECTROPHOTOMETRIC STUDY OF O2 DELIVERY [J].

BALABAN, RS ;

SOLTOFF, SP ;

STOREY, JM ;

MANDEL, LJ .

AMERICAN JOURNAL OF PHYSIOLOGY, 1980, 238 (01) :F50-F59

[2]

Bergmeyer H., 1963, METHOD ENZYMAT AN

[3] EFFECTS OF HEXACHLOROBUTADIENE (HCBD) ON RENAL-FUNCTION AND RENAL ORGANIC ION-TRANSPORT IN THE RAT [J].

BERNDT, WO ;

MEHENDALE, HM .

TOXICOLOGY, 1979, 14 (01) :55-65

[4]

CHANCE B, 1956, ADV ENZYMOL REL S BI, V17, P65

[5]

DUPRAT P, 1978, ACTA PHARMACOL TOX, V43, P346

[6] RENAL PROCESSING OF GLUTATHIONE CONJUGATES - ROLE IN NEPHROTOXICITY [J].

ELFARRA, AA ;

ANDERS, MW .

BIOCHEMICAL PHARMACOLOGY, 1984, 33 (23) :3729-3732

[7]

GORNALL AG, 1949, J BIOL CHEM, V177, P751

[8] STRUCTURE ACTIVITY STUDIES OF THE NEPHROTOXIC AND MUTAGENIC ACTION OF CYSTEINE CONJUGATES OF CHLOROALKENES AND FLUOROALKENES [J].

GREEN, T ;

ODUM, J .

CHEMICO-BIOLOGICAL INTERACTIONS, 1985, 54 (01) :15-31

[9] DETERMINATION OF GLUTATHIONE AND GLUTATHIONE DISULFIDE USING GLUTATHIONE-REDUCTASE AND 2-VINYLPYRIDINE [J].

GRIFFITH, OW .

ANALYTICAL BIOCHEMISTRY, 1980, 106 (01) :207-212

[10]

HARRIS SI, 1981, J BIOL CHEM, V256, P319

← 1 2 3 →