INSULIN INDUCES CELL-ADHESION AND NORMAL FLATTENED MORPHOLOGY IN KREBS-II ASCITES TUMOR-CELLS

被引:8
作者
PRYME, IF [1 ]
HESKETH, JE [1 ]
机构
[1] ROWETT RES INST,BUCKSBURN AB2 9SB,ABERDEEN,SCOTLAND
基金
英国惠康基金;
关键词
D O I
10.1016/0309-1651(90)90095-G
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Insulin induced Krebs II ascites cells to attach to the substratum and to adopt a flattened morphology associated with normal adhesion and movement. The changes were associated with a reorganization of cellular actin. The results show that insulin has important effects on cell structure and morphology. Insulin may thus be involved in the nutritional control of normal and malignant growth. © 1990.
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页码:447 / 455
页数:9
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