MITOTIC DISASSEMBLY OF THE MAMMALIAN GOLGI-APPARATUS

被引：31

作者：

WARREN, G

LEVINE, T

MISTELI, T

机构：

[1] Imperial Cancer Research Fund, London, WC2A 3PX

[2] Cold Spring Harbor Laboratory, Cold Spring Harbor

来源：

TRENDS IN CELL BIOLOGY | 1995年 / 5卷 / 11期

关键词：

D O I：

10.1016/S0962-8924(00)89094-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A cell-free system that mimics mitotic fragmentation of Golgi stacks has provided a working model for the disassembly process. Two distinct pathways, one COP-dependent and one COP-independent, act on Golgi stacks to give rise to two types of end products: transport vesicles and larger, more heterogeneous vesicles and tubules. We suggest that both mitotic end products result from enhanced fission of Golgi membranes under conditions where membrane fusion is generally inhibited.

引用

收藏

页码：413 / 416

页数：4

相关论文

共 34 条

[1] PHOSPHORYLATION OF 2 SMALL GTP-BINDING PROTEINS OF THE RAB FAMILY BY P34CDC2 [J].

BAILLY, E ;

MCCAFFREY, M ;

TOUCHOT, N ;

ZAHRAOUI, A ;

GOUD, B ;

BORNENS, M .

NATURE, 1991, 350 (6320) :715-718

[2] TRANSCYTOSIS-ASSOCIATED PROTEIN (TAP)/P115 IS A GENERAL FUSION FACTOR REQUIRED FOR BINDING OF VESICLES TO ACCEPTOR MEMBRANES [J].

BARROSO, M ;

NELSON, DS ;

SZTUL, E .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (02) :527-531

[3]

BIRKY CW, 1983, INT REV CYTOL, P49

[4] ADP-RIBOSYLATION FACTOR AND COATOMER COUPLE FUSION TO VESICLE BUDDING [J].

ELAZAR, Z ;

ORCI, L ;

OSTERMANN, J ;

AMHERDT, M ;

TANIGAWA, G ;

ROTHMAN, JE .

JOURNAL OF CELL BIOLOGY, 1994, 124 (04) :415-424

[5] THE KARYOGAMY GENE KAR2 AND NOVEL PROTEINS ARE REQUIRED FOR ER-MEMBRANE FUSION [J].

LATTERICH, M ;

SCHEKMAN, R .

CELL, 1994, 78 (01) :87-98

[6] COATOMER IS ESSENTIAL FOR RETRIEVAL OF DILYSINE-TAGGED PROTEINS TO THE ENDOPLASMIC-RETICULUM [J].

LETOURNEUR, F ;

GAYNOR, EC ;

HENNECKE, S ;

DEMOLLIERE, C ;

DUDEN, R ;

EMR, SD ;

RIEZMAN, H ;

COSSON, P .

CELL, 1994, 79 (07) :1199-1207

[7] MITOTIC GOLGI FRAGMENTS IN HELA-CELLS AND THEIR ROLE IN THE REASSEMBLY PATHWAY [J].

LUCOCQ, JM ;

BERGER, EG ;

WARREN, G .

JOURNAL OF CELL BIOLOGY, 1989, 109 (02) :463-474

[8] A MITOTIC FORM OF THE GOLGI-APPARATUS IN HELA-CELLS [J].

LUCOCQ, JM ;

PRYDE, JG ;

BERGER, EG ;

WARREN, G .

JOURNAL OF CELL BIOLOGY, 1987, 104 (04) :865-874

[9] THE SMALL GTP-BINDING PROTEIN RAB6 FUNCTIONS IN INTRA-GOLGI TRANSPORT [J].

MARTINEZ, O ;

SCHMIDT, A ;

SALAMERO, J ;

HOFLACK, B ;

ROA, M ;

GOUD, B .

JOURNAL OF CELL BIOLOGY, 1994, 127 (06) :1575-1588

[10] A ROLE FAR TUBULAR NETWORKS AND A COP I-INDEPENDENT PATHWAY IN THE MITOTIC FRAGMENTATION OF GOLGI STACKS IN A CELL-FREE SYSTEM [J].

MISTELI, T ;

WARREN, G .

JOURNAL OF CELL BIOLOGY, 1995, 130 (05) :1027-1039

← 1 2 3 4 →