CYTOGENETIC FINDINGS IN A CASE OF NODULAR FASCIITIS OF THE BREAST

被引：36

作者：

BIRDSALL, SH ^{[1
]}

SHIPLEY, JM ^{[1
]}

SUMMERSGILL, BM ^{[1
]}

BLACK, AJM ^{[1
]}

JACKSON, P ^{[1
]}

KISSIN, MW ^{[1
]}

GUSTERSON, BA ^{[1
]}

机构：

[1] ROYAL SUSSEX CTY HOSP,GUILDFORD,SURREY,ENGLAND

来源：

CANCER GENETICS AND CYTOGENETICS | 1995年 / 81卷 / 02期

关键词：

D O I：

10.1016/0165-4608(94)00229-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report the cytogenetic findings in a case of nodular fasciitis of the breast. The abnormalities found in all 11 metaphases available for analysis were -2, -2, -13,der(15)t(2;15)(q31;q26), +der(?) t(?;2), +mar1, +mar2. Other consistent abnormalities were also identified. Fluorescence in situ hybridization (FISH) was used to confirm the origin of some of the chromosomes. A large acrocentric chromosome was confirmed to be derived from chromosome 15 with chromosome 2 material translocated onto the q arm. The metacentric der(?)t(?;2) was demonstrated to have part of chromosome 2 on the q arm. No other chromosome 2 material was found. Eight of 11 cells were tetraploid and had two copies of a del(6)(q16q24).

引用

页码：166 / 168

页数：3

共 19 条

[1] IMMUNOCYTOCHEMICAL LOCALIZATION OF THE ECTOENZYME AMINOPEPTIDASE-N IN THE HUMAN BREAST [J].