KINETIC STUDY OF DEHALOGENATION OF 5-CHLORO-IODOURACIL, 5-BROMO-IODOURACIL, AND 5-IODOURACIL IN AQUEOUS-SOLUTIONS OF SODIUM BISULFITE

被引：33

作者：

RORK, GS ^{[1
]}

PITMAN, IH ^{[1
]}

机构：

[1] UNIV KANSAS,SCH PHARM,DEPT PHARM CHEM,LAWRENCE,KS 66044

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1975年 / 97卷 / 19期

关键词：

D O I：

10.1021/ja00852a040

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：5559 / 5565

页数：7

共 15 条

[1]

Albert A., 1962, IONIZATION CONSTANTS

[2]

BERENS K, 1963, ACTA BIOCHIM POL, V10, P25

[3] CHEMICAL-EQUILIBRIA IN SOLUTIONS OF BISULFITE SALTS [J].

BOURNE, DWA ;

HIGUCHI, T ;

PITMAN, IH .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1974, 63 (06) :865-868

[4] LINEAR FREE-ENERGY RELATIONSHIPS GOVERNING COVALENT ADDITION OF NUCLEOPHILIC-REAGENTS TO A NITROGEN-CONTAINING HETEROAROMATIC MOLECULE [J].

CHO, MJ ;

PITMAN, IH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1974, 96 (06) :1843-1849

[5] DETERMINATION OF THERMODYNAMICS OF HALOGEN GROUPS IN SOLUTIONS OF DRUG MOLECULES [J].

DAVIS, SS .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1973, 25 (10) :769-778

[6]

FLOURREY JL, 1972, B SOC CHIM FR, P4580

[7] KINETICS AND MECHANISMS OF HYDROLYSIS OF 5-HALOURACILS [J].

GARRETT, ER ;

NESTLER, HJ ;

SOMODI, A .

JOURNAL OF ORGANIC CHEMISTRY, 1968, 33 (09) :3460-&

[8] ELIMINATION OF BISULFITE ION FROM A SERIES OF URACIL-BISULFITE ADDUCTS - EVIDENCE FOR A 2-STEP MECHANISM [J].

RORK, GS ;

PITMAN, IH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1974, 96 (14) :4654-4663

[9] BISULFITE-ION-CATALYZED DEGRADATION OF FLUOROURACIL [J].

RORK, GS ;

PITMAN, IH .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1975, 64 (02) :216-220

[10] KINETIC STUDY OF DEHALOGENATION OF 5-HALO-5,6-DIHYDROURACILS IN AQUEOUS-SOLUTIONS OF SODIUM BISULFITE [J].

RORK, GS ;

PITMAN, IH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1975, 97 (19) :5566-5572

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