ASSOCIATION OF MULTIPLE COPIES OF THE N-MYC ONCOGENE WITH RAPID PROGRESSION OF NEUROBLASTOMAS

被引：1871

作者：

SEEGER, RC

BRODEUR, GM

SATHER, H

DALTON, A

SIEGEL, SE

WONG, KY

HAMMOND, D

机构：

[1] CHILDRENS CANC STUDY GRP, LOS ANGELES, CA USA

[2] WASHINGTON UNIV, SCH MED, DEPT PEDIAT, ST LOUIS, MO 63110 USA

[3] WASHINGTON UNIV, SCH MED, DEPT GENET, ST LOUIS, MO 63110 USA

[4] CHILDRENS HOSP, DIV HEMATOL ONCOL, LOS ANGELES, CA 90027 USA

[5] UNIV CINCINNATI, COLL MED, DEPT PEDIAT, CINCINNATI, OH 45221 USA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 1985年 / 313卷 / 18期

关键词：

D O I：

10.1056/NEJM198510313131802

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1111 / 1116

页数：6

共 43 条

[1] HOMOGENEOUSLY STAINING CHROMOSOMAL REGIONS CONTAIN AMPLIFIED COPIES OF AN ABUNDANTLY EXPRESSED CELLULAR ONCOGENE (C-MYC) IN MALIGNANT NEUROENDOCRINE CELLS FROM A HUMAN-COLON CARCINOMA [J].

ALITALO, K ;

SCHWAB, M ;

LIN, CC ;

VARMUS, HE ;

BISHOP, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (06) :1707-1711

[2] ABERRANT EXPRESSION OF AN AMPLIFIED C-MYB ONCOGENE IN 2 CELL-LINES FROM A COLON-CARCINOMA [J].

ALITALO, K ;

WINQVIST, R ;

LIN, CC ;

DELACHAPELLE, A ;

SCHWAB, M ;

BISHOP, JM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (14) :4534-4538

[3] CELLULAR ONCOGENES AND RETROVIRUSES [J].

BISHOP, JM .

ANNUAL REVIEW OF BIOCHEMISTRY, 1983, 52 :301-354

[4]

BRESLOW N, 1971, CANCER RES, V31, P2098

[5] AMPLIFICATION OF N-MYC IN UNTREATED HUMAN NEUROBLASTOMAS CORRELATES WITH ADVANCED DISEASE STAGE [J].

BRODEUR, GM ;

SEEGER, RC ;

SCHWAB, M ;

VARMUS, HE ;

BISHOP, JM .

SCIENCE, 1984, 224 (4653) :1121-1124

[6] AMPLIFICATION OF ENDOGENOUS MYC-RELATED DNA-SEQUENCES IN A HUMAN MYELOID-LEUKEMIA CELL-LINE [J].

COLLINS, S ;

GROUDINE, M .

NATURE, 1982, 298 (5875) :679-681

[7] REARRANGEMENT AND AMPLIFICATION OF C-ABL SEQUENCES IN THE HUMAN CHRONIC MYELOGENOUS LEUKEMIA-CELL LINE K-562 [J].

COLLINS, SJ ;

GROUDINE, MT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (15) :4813-4817

[8] DO INFANTS WITH STAGE IV-S NEURO-BLASTOMA NEED TREATMENT [J].

EVANS, AE ;

BAUM, E ;

CHARD, R .

ARCHIVES OF DISEASE IN CHILDHOOD, 1981, 56 (04) :271-274

[9]

EVANS AE, 1971, CANCER, V27, P374, DOI 10.1002/1097-0142(197102)27:2<374::AID-CNCR2820270221>3.0.CO

[10]

2-G

← 1 2 3 4 5 →