CONTRALATERAL CEREBELLAR DIASCHISIS 7 HOURS AFTER MCA-OCCLUSION IN PRIMATES

被引：18

作者：

DETTMERS, C

HARTMANN, A

ROMMEL, T

HARTMANN, S

PAPPATA, S

BARON, JC

机构：

[1] UNIV COLOGNE,NEUROCHIRURG KLIN,D-51109 COLOGNE,GERMANY

[2] DRIPP,CEA,SERV HOSP FREDERIC JOLIOT,ORSAY,FRANCE

[3] INSERM,U320,F-14021 CAEN,FRANCE

来源：

NEUROLOGICAL RESEARCH | 1995年 / 17卷 / 02期

关键词：

MICROSPHERES; TETRAZOLIUM CHLORIDE; EXPERIMENTAL INFARCTION; FOCAL CEREBRAL ISCHEMIA; MCA-OCCLUSION; DIASCHISIS; PRIMATES; CEREBRAL BLOOD FLOW;

D O I：

10.1080/01616412.1995.11740297

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

2,3,5-triphenyltetrazoliumchloride (TTC) as an indicator of mitochondrial function in combination with regional cerebral blood flow measurements was used in six baboons 6.9 +/- 7.2 h after permanent occlusion of the left middle cerebral artery. Staining with TTC was compared with blood flow data obtained during normocapnia using the microsphere method. Five animals showed a focal area of unstained tissue in the left middle cerebral artery territory. Mean blood flow in the unstained area was 28.3 +/- 15.4 ml min(-1) 100 g(-1). Five of 6 animals showed a significant decrease of contralateral cerebellar blood flow in the presence of normal TTC staining. We conclude that at this early stage of infarction contralateral cerebellar diaschisis is caused by functional deactivation.

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收藏

页码：109 / 112

页数：4

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