NEURON SPECIFIC ENOLASE (NSE) IN SERUM OF PATIENTS WITH MALIGNANT-MELANOMA

被引：17

作者：

WIBE, E ^{[1
]}

PAUS, E ^{[1
]}

AAMDAL, S ^{[1
]}

机构：

[1] NORWEGIAN RADIUM HOSP,CENT LAB,N-0310 OSLO 3,NORWAY

来源：

CANCER LETTERS | 1990年 / 52卷 / 01期

关键词：

malignant melanoma; neuron specific enolase; NSE; serum marker;

D O I：

10.1016/0304-3835(90)90073-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Serial measurements of serum NSE were performed in 63 patients with metastatic melanoma. NSE was measured by a sensitive immunoradiometric assay based upon monoclonal anti-bodies with monodisperse magnetizable particles as the solid phase. Increased NSE values were found in 30 patients (48%) during the course of the disease. In 10 patients serum NSE normalized during systemic therapy. In 11 patients with initial normal serum NSE, the marker values became elevated as the tumor progressed. © 1990.

引用

页码：29 / 31

页数：3

共 12 条

[1] NEURON SPECIFIC ENOLASE - AN AID TO THE DIAGNOSIS OF MELANOMA AND NEURO-BLASTOMA [J].