PROSPECTIVE-STUDY OF FOOD-INTAKE AND NUTRITIONAL-STATUS IN HIV-INFECTION

被引:10
作者
FOSKETT, M
KAPEMBWA, M
SEDGWICK, P
GRIFFIN, GE
机构
[1] Division of Communicable Diseases, St. George's Hospital Medical School, London, SW17 OQT, Blackshaw Road, Tooting
关键词
HIV INFECTION; NUTRITIONAL STATUS; NUTRITIONAL ASSESSMENT; WEIGHED FOOD INTAKE; ANTHROPOMETRIC MEASUREMENTS; FAT ABSORPTION;
D O I
10.1111/j.1365-277X.1991.tb00092.x
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Weight loss is a common feature of Human Immunodeficiency Virus (HIV) infection. The aetiology of such weight loss is multifactorial; however the relative importance of factors involved is unknown. In order to test the hypothesis that a gross reduction of food intake is one of the factors responsible for weight loss seen in HIV disease, we prospectively measured food intake for 7 days in 11 male HIV antibody positive subjects and nine male control subjects. Anthropometric measurements were taken to assess nutritional status and fat absorption was assessed using l-C-14 Triolein breath test. In the 3 months preceding the study mean weight loss was 3.9 +/- 1.2 kg. (s.e.m.) for the HIV antibody positive group. Protein and energy intakes were not significantly different between the two groups. HIV infected subjects had significantly lower mid-arm muscle circumference (MAMC) and grip strength (GS). Fat malabsorption of a minor degree was detected in only three subjects. These data suggest that constitutionally well HIV infected subjects have reduced MAMC and GS in the face of apparently adequate protein and energy intakes.
引用
收藏
页码:149 / 154
页数:6
相关论文
共 26 条
  • [1] Ash S.A., Griffin G.E., The effects of parenteral nutrition on protein turnover in endotoxaemic rats, Clinical Science, 76, pp. 659-666, (1989)
  • [2] Bingham S.A., The dietary assessment of individuals
  • [3] methods, accuracy, new techniques and recommendations, Nutrition Abstracts and Reviews (Series A), 57, pp. 705-742, (1987)
  • [4] Classification system for human T‐lymphotropic virus type III/lymphadenopathy‐associated virus infections, Annals of Internal Medicine, 105, pp. 234-237, (1986)
  • [5] Chandra R.K., Nutrition, Immunity and Infection: present knowledge and future directions, Lancet, 1, pp. 688-691, (1983)
  • [6] Hickey M.S., Weaver K.E., Nutritional management of patients with ARC or AIDS, Gastroenterology Clinics of North America, 17, pp. 545-561, (1988)
  • [7] Holmes G.K.T., Hill P.G., Do we still need to measure faecal fat? (Editorial), Br Med J, 286, (1988)
  • [8] Hunt D.R., Rowlands B.J., Johnston D., Hand Grip Strength‐A simple prognostic indicator in surgical patients, Journal of Parenteral and Enteral Nutrition, 9, pp. 701-704, (1985)
  • [9] Jelliffe D.B., Assessment of nutritional status of the community—with special reference to field surveys in developing regions of the world, (1966)
  • [10] Kotler D.P., Gaetz H.P., Lange M., Klein E.B., Holt P.R., Enteropathy associated with the acquired immunodeficiency syndrome, Annals of Internal Medicine, 101, pp. 421-428, (1984)