COAGGREGATION STUDIES OF THE EUBACTERIUM SPECIES

被引：24

作者：

GEORGE, KS

FALKLER, WA

机构：

[1] Department of Microbiology, University of Maryland Dental School, Baltimore

来源：

ORAL MICROBIOLOGY AND IMMUNOLOGY | 1992年 / 7卷 / 05期

关键词：

EUBACTERIUM; FUSOBACTERIUM-NUCLEATUM; DENTAL PLAQUE; PERIODONTAL DISEASE; ECOLOGY; COAGGREGATION;

D O I：

10.1111/j.1399-302X.1992.tb00590.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Eubacterium species are gram-positive anaerobic rods that are frequently isolated from subgingival plaque of periodontal pockets. Five Eubacterium species were tested for their ability to coaggregate with 33 oral bacterial strains. Using visual and turbidimetric assays, coaggregation was observed among Eubacterium brachy, Eubacterium nodatum, Eubacterium alactolyticum and Eubacterium limosum strains only when tested with Fusobacterium nucleatum strains; Eubacterium saburreum displayed only weak coaggregation ability. Coaggregation between F. nucleatum and the Eubacterium species was observed over a wide range of concentrations of each organism. The F. nucleatum strains contained a beat labile and the Eubacterium species a heat stabile coaggregation receptor. Arginine, histidine, lysine and glycine inhibited the coaggregation between F nucleatum and the Eubacterium species. Sugars and other amino acids tested did not inhibit the observed coaggregation. Rabbit anti-F nucleatum serum completely inhibited coaggregation, but anti-E. brachy serum and normal rabbit serum did not. As these anaerobic microorganisms are frequently isolated from the same oral lesions, the surface interactions observed may be important in the pathogenesis of these polymicrobic infections.

引用

页码：285 / 290

页数：6

共 39 条

[1]

Beachey EH, Courtney HS, Bacterial adherence: the attachment of Group A streptococci to mucosal surfaces, Rev Infect Dis, 9, (1987)

[2]

Ciardi JE, McCray GFA, Kolenbrander PE, Lau A., Cell‐to‐cell interaction of Streptococcus sanguis and Propionibacterium acnes on saliva‐coated hydroxy‐apatite, Infect Immun, 55, pp. 1441-1446, (1987)

[3]

Cisar JO, Brennan MJ, Sandberg AL, Lectin‐specific interaction of Actinomyces fimbriae with oral streptococci, Molecular basis of oral microbial adhesion, pp. 159-163, (1985)

[4]

Cisar JO, Coaggregation reactions between oral bacteria: studies of specific cell‐to‐cell adherence mediated by microbial lectins, Host parasite interactions in periodontal diseases, pp. 121-131, (1982)

[5]

Cisar JO, Kolenbrander PE, Mclntire FC, Specificity of coaggregation reactions between human oral streptococci and strains of Actinomyces viscosus or Actinomyces naeslundii, Infect Immun, 24, pp. 742-752, (1979)

[6]

Dehazya P, Coles RS, Agglutination of human erythrocytes by Fusobacterium nucleatum: factors influencing hemagglutination and some characteristics of the agglutinin, J Bacteriol, 143, pp. 205-211, (1980)

[7]

Dzink JL, Socransky SS, Haffajee AD, The predominant cultivable microbiota of active and inactive lesions of destructive periodontal diseases, J Clin Periodontol, 15, pp. 316-323, (1988)

[8]

Ellen RP, Grove DA, Bacteroides gingivalis vesicles bind to and aggregate Actinomyces viscosus, Infect Immun, 57, pp. 1618-1620, (1989)

[9]

Ellen RP, Balcerzak-Raczkowski IB, Interbacterial aggregation of Actinomyces naeslundii and dental plaque streptococci, J Periodont Res, 12, pp. 11-20, (1977)

[10]

Gibbons RJ, Nygaard M., Interbacterial aggregations of plaque bacteria, Arch Oral Biol, 15, pp. 1397-1400, (1970)

← 1 2 3 4 →