STEREOCHEMICAL FEATURES OF THE STEREOSELECTIVE INTERACTION BETWEEN (R)--7,7'-BIS(1-PROPEN)-3-OXY)-2,2'-DIHYDROXY-1,1'-BINAPHTYL OR (S)-7,7'-BIS(1-PROPEN)-3-OXY)-2,2'-DIHYDROXY-1,1'-BINAPHTHYL AND QUININE

被引：8

作者：

UCCELLOBARRETTA, G ^{[1
]}

PINI, D ^{[1
]}

ROSINI, C ^{[1
]}

SALVADORI, P ^{[1
]}

机构：

[1] CNR,CTR STUDIO MACROMOLEC STEREORDINATE OTTICAMENTE A,DIPARTIMENTO CHIM & CHIM IND,I-56126 PISA,ITALY

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 666卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(94)80416-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Quinine forms diastereoisomeric adducts with the enantiomers of 7,7'-bis(1-propen-3-oxy)-2,2'-dihydroxy-1,1'-binaphthyl. Their stereochemistry in solution was investigated by H-1 NMR spectroscopy at various temperatures and by analysis of the intermolecular H-1{H-1} nuclear Overhauser effect enhancements. A hypothesis for the chiral discrimination mechanism involved in the HPLC separation of this binaphthyl compound on a quinine-based chiral stationary phase is given.

引用

页码：541 / 548

页数：8

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