STRATEGY IN DRUG DESIGN - CLUSTER ANALYSIS AS AN AID IN SELECTION OF SUBSTITUENTS

被引：181

作者：

HANSCH, C

UNGER, SH

FORSYTHE, AB

机构：

[1] POMONA COLL,DEPT CHEM,CLAREMONT,CA 91711

[2] UNIV CALIF,DEPT BIOMATH,LOS ANGELES,CA 90024

来源：

关键词：

D O I：

10.1021/jm00269a004

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1217 / 1222

页数：6

共 26 条

[1] Anderson TW., 1958, INTRO MULTIVARIATE S
[2] BURGER A, 1970, MEDICINAL CHEMISTRY, V1
[3] PREDICTABILITY OF CORRELATIONS BETWEEN IN-VITRO TETRACYCLINE POTENCIES AND SUBSTITUENT INDICES
CAMMARAT.A
YAU, SJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1970, 13 (01) : 93 - &
[4] CRAIG PN, 1972, ADV CHEM SER, P115
[5] INTERDEPENDENCE BETWEEN PHYSICAL PARAMETERS AND SELECTION OF SUBSTITUENT GROUPS FOR CORRELATION STUDIES
CRAIG, PN
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (08) : 680 - &
[6] Exner O., 1972, ADV LINEAR FREE ENER
[7] MULTICOLLINEARITY IN REGRESSION ANALYSIS - PROBLEM REVISITED
FARRAR, DE
GLAUBER, RR
[J]. REVIEW OF ECONOMICS AND STATISTICS, 1967, 49 (01) : 92 - 107
[8] HANSCH C, 1971, ANN NY ACAD SCI, V186, P235
[9] HANSCH C, 1972, ADV CHEM SER, P20
[10] HANSCH C, 1972, CANCER CHEMOTH REP 1, V56, P433