DELAYED TIME COURSE OF IRRITATION BY SODIUM LAURYL SULFATE - OBSERVATIONS ON THRESHOLD REACTIONS

被引：55

作者：

BRUYNZEEL, DP ^{[1
]}

VANKETEL, WG ^{[1
]}

SCHEPER, RJ ^{[1
]}

VONBLOMBERGVANDERFLIER, BME ^{[1
]}

机构：

[1] FREE UNIV AMSTERDAM HOSP, DEPT PATHOL, 1081 HV AMSTERDAM, NETHERLANDS

来源：

CONTACT DERMATITIS | 1982年 / 8卷 / 04期

关键词：

D O I：

10.1111/j.1600-0536.1982.tb04205.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Irritant reactions to sodium lauryl sulfate were induced on the backs of 20 [human] volunteers by patch test occlusion for 24 h. Different concentrations ranging from 0.25-2% were used, the lowest concentration being borderline irritant. The skin tests were read at 24, 48 and 72 h. Both the % of responding individuals and the intensity of the skin reactions were maximal at 48 h for all test concentrations. Irritants may provoke inflammatory reactions which are not completely developed after 24 h, and are very similar to allergic patch test reactions.

引用

页码：236 / 239

页数：4

共 16 条

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